Saturday, October 12, 2019
An Unwilling Hamlet Essay -- William Shakespeare
à à à In the play, Hamlet, by William Shakespeare, the main character, Hamlet is an unwilling creature. In having to enter and act in the world of his uncle, Hamlet becomes an unwilling creature of that world. When he chooses to obey the ghost's command and revenge his father, Hamlet accepts the inevitability that he must become part of this world. As the ripple of original vengeful intent widens and Hamlet is slowly but surely entangled in Claudius'à brutal world à through his madness, his murders, his plots, his relationship with other characters and his revelations on life and more importantly, death. à à à à à à à à à à à à Even before the ghost urges Hamlet to avenge his death, Hamlet teeters on the edge of his uncle's brutal world. While never evil in intent Hamlet is simply one of the finest tragic heroes. Caught between his agony of mind and indecision Hamlet's nature is neither treacherous like Claudius' nor rash like Laertes'. This combination of values carries only tragedy when one such as Hamlet suffers such a fate as he did. Prior to his dead father's prompting, Hamlet is already devoured by melancholy over the loss of Old Hamlet and his mother's "o'er hasty" marriage to Claudius. This suggests that Hamlet was already inexorably linked to his Uncle's brutal world.à "It is not, nor it cannot come to good."à (Act1, Scene2) à Hamlet also feels jealousy towards his mother as their relationship goes beyond that of a normal parent/child relationship. While perhaps not sexual, their mere fifteen years age difference has enclosed them in a very close-knit co-dependant affair.à "You are the Queen, your husband's brother's wife, And, would it not so, you are my mother." (Act3, Scene4)à This jealousy and hatred Hamlet feels is close... ...d.â⬠à Works Cited delman, Janet. 1985. 'Male Bonding in Shakespeare's Comedies.' In Shakespeare's Rough Magic: Renaissance Essays in Honor of C.L. Barber, edited by Peter Erickson and Coppà ©lia Kahn. Cranbury and London: Associated University Presses, 73-103. Adelman, Janet. 1992. Suffocating Mothers: Fantasies of Maternal Origin in Shakespeare's plays, 'Hamlet' to 'The Tempest'. London and New York: Routledge. Alexander, Nigel. 1971. Poison, Play and Duel: A Study in Hamlet. London: Routledge. Barber, C. L., and Wheeler, Richard P. 1986. The Whole Journey: Shakespeare's Power of Development. Berkeley, Los Angeles, London: University of California Press. Partridge, Eric. 1947. Shakespeare's Bawdy. London and New York: Routledge. Rubinstein, Frankie. 1984. A Dictionary of Shakespeare's Sexual Puns and their Significance. London: MacMillan.
Friday, October 11, 2019
Blackberry
The product that we have chosen Is Blackberry smartened. The term BlackBerry refers to a line of wireless handheld devices and services designed and marketed by BlackBerry Limited, formerly known as Research In Motion Limited (RIM). Target Markets: Its target markets are Business professionals who opt for high security text messaging and E-mails.Productivity of BlackBerry and why It has Targeted the business professionals: During the early 20005, Research In Motion's Blackberry's were the most popular smartness In the world; since then, though, RIM's market hare In the Industry has been eaten up by Apple's Phone and Google's Android. Still, the BlackBerry remains a popular model amongst business professionals, as It offers not only a fast and powerful processor, but also Blackberry's Enterprise Services.This corporate email system makes it easy and convenient for professionals on-the-go to connect to their respective corporate email accounts and is undedicated by other major smartene d lines like the phone and Android. Visualize and risk taking strategy: Blackberry main strategy is how secure the customer data and E-mails with this agenda they mainly targeted the business professionals which can be called as a Niche market . With the development of new technology and o. The Android smart phones and phone devices which made the technology user friendly with millions of APS. These Android mobiles and phone has targeted each and every individual right from students who are interested in playing games but also the business professionals by integrating and synchronizing treachery in Motion's future grows iffier each quarter as it signs on fewer new customers and has had to discount large numbers of BlackBerry smartness and Playback tablets to clear inventory.The company revealed today that its revenue dropped 25 percent in the last fiscal quarter versus a year earlier, a decrease of $5. 6 billion. RIM executives said they were willing to explore other business models , such as licensing all or some BlackBerry technologies to other companies. Some Investors have suggested that RIM license or sell access to Its secure messaging network or Its BlackBerry Messenger instant messaging service.RIM has licensed there IBM services and made the app available In android and Los this made the Blackberry unique. Santos Krishna Surest shogun Blackberry By Crackerjacks messaging and E-mails. Productivity of BlackBerry and why it has Targeted the business professionals: During the early sass, Research in Motion's Blackberry's were the most popular smartness in the world; since then, though, RIM's market share in the industry has been eaten up by Apple's phone and Google's Android.Still, the BlackBerry remains a popular model amongst business professionals, as it offers not only a fast and powerful processor, but also BlackBerry's Enterprise agenda they mainly targeted the business professionals which can be called as a phones and ââ¬Ëphone devices which made the technology user friendly with millions of PlayBook tablets to clear inventory.The company revealed today that its revenue as licensing all or some BlackBerry technologies to other companies. Some investors have suggested that RIM license or sell access to its secure messaging network or its services and made the app available in android and ISO this made the Blackberry
Thursday, October 10, 2019
Emerson concepts in ââ¬ËKite Runnerââ¬â¢ and ââ¬ËGiovanniââ¬â¢s Roomââ¬â¢ Essay
ââ¬Å"Society everywhere is in conspiracy against the manhood of every one of its members. â⬠(Emerson. 2) Thus we live in a world, where in order to fit we must ââ¬Ëconformââ¬â¢ but Emerson believes that ââ¬Å"whoso would be a man must be a nonconformist,â⬠(2) and that ââ¬Å"nothing is at last sacred but the integrity of your own mind. â⬠(2) Self reliance and independence of thought, which are fundamental to Emersonââ¬â¢s perspective, are integral to the understanding and analysis of the characters in ââ¬ËThe Kite Runnerââ¬â¢ (Hosseini, 2003) and ââ¬ËGiovanniââ¬â¢s Roomââ¬â¢ (Baldwin, 1956). ââ¬ËThe Kite Runner,ââ¬â¢ is a tale of two boys in 1970ââ¬â¢s Kabul; growing up amidst discrimination, bigotry and class structure in society ââ¬â in this case Afghan society ââ¬â Hassan, a Hazara ââ¬â a minority group of Afghanis who follow Islamic beliefs called Shiââ¬â¢a ââ¬â although a friend and half-brother, is a lower-class servant to Amir. Amir, a Pushtun ââ¬â the majority, who believe they are a better class than the Hazara and who follow the Sunn sect of Islam ââ¬â although raised in the same household and sharing the same wet nurse as Hassan, lives in a different sphere of existence. Amir is the legitimate son of Baba, a prominent and wealthy man, whereas Hassan is the illegitimate one and raised by Babaââ¬â¢s servant. Both lost their mothers ââ¬â Amir at birth and Hassan a week after birth, when she ran ââ¬Å"off with a clan of singers and dancers. â⬠(Hosseini 4) ââ¬Å"For nonconformity the world whips you with its displeasure,â⬠(Emerson 4) and thus Baba, rather than be subjected to the displeasures of his society, opts to conform to its rules and customs that ââ¬Å"loves not realities and creators, but names and customs,â⬠(Emerson 2) and not reveal that Hassan is his son by a Hazara woman. His justice, or what Emerson characterizes as ââ¬Ëcompensationââ¬â¢ (The Internet Encyclopedia of Philosophy) is the loss of Hassan and his love. This same class difference between Amir and Hassan, largely dictates and limits their relationship. ââ¬Å"It is easy enough for a firm man who knows the world to brook the rage of the cultivated classes,â⬠(Emerson 4) and Hassan, the victim of such discrimination and class structure, remains completely devoted and loyal to Amir, both as his servant and as his friend. He shows his loyalty when he and Amir are terrorized by Assef, ââ¬Å" a word for the creature that Assef was â⬠¦Ã¢â¬â¢sociopathââ¬â¢ (Hosseini 25-26) who admires Hitler for eliminating the Jews and with whom he aims to emulate by destroying the Hazaras. Hassan stands up to Assef and his friends. Although frightened, he holds ââ¬Å"the slingshot pointed directly at Assefââ¬â¢s faceâ⬠(Hosseini 28) and shouts ââ¬Å"if you move, theyââ¬â¢ll have to change your nickname from Assef the ââ¬ËEar Eaterââ¬â¢ to ââ¬ËOne-Eyed Assef. â⬠(Hosseini 29) Assef, never forgetting a slight, plots revenge. Just as Hassan makes Amirââ¬â¢s breakfast, folds his clothes, and cleans his room, so does he cater to Amir in kite tournaments. Even though Hassan shares in the excitement of kite fighting, he does not actually have control over the kite. Hassan may help the kite ââ¬Å"lift-and-dive,â⬠but Amir is the one who claims a victory. Hassan may catch a cherished rival kite and hold it in his arms, but always to bring it back to Amir, to whom it then belongs. His joy is explicit, special, and secondary just like his experience of wealth and privilege while living in Babaââ¬â¢s household. So it is that Hassan is subjected to rape because of his nonconformity to his position as a Hazara and he relies on himself to ââ¬Å"go alone; to refuse the good models. â⬠(Emerson 5) Assef and his friends attack Hassan after he runs for the ââ¬Ëblue kiteââ¬â¢ but although terrified of what is going to happen to him he claims ââ¬Å"Amir agha won the tournament and I ran this kite for him. I ran it fairly, this is his kite. â⬠ââ¬Å"Amir agha and I are friends. â⬠(Hosseini 50) Hassan is brutely raped by Assef but never gives up the kite and brings it back for Amir. Later, when the Taliban came to ââ¬Å"investigate and interrogated Hassanâ⬠(Hosseini 149) and ordered him to leave the house ââ¬â Amirââ¬â¢s fatherââ¬â¢s house ââ¬â he again shows his loyalty to Amir by protesting. The Taliban ââ¬Å"ordered him to kneel â⬠¦ and shot him in the back of the head. â⬠(Hosseini 150) Hassan dies because he ââ¬Å"accepted the divine place that providence hadâ⬠found for him; (Emerson 1) he had violated the social expectations of conformity by favouring ââ¬Å"self reliance â⬠¦ its aversionâ⬠(Emerson 2) by standing up to his aggressors in loyalty to Amir. Amir, contrary to Hassan, lacks self trust and conforms totally to society, and although enjoying time spent with Hassan, never really calls him his friend. When confronted with Assef the first time he shows his cowardice by wanting to tell Assef that Hassan is ââ¬Å"not my friend,â⬠ââ¬Å"heââ¬â¢s my servant. â⬠(Hosseini 28) It is ironic that when Hassan stands up for Amir against Assef, and calls him ââ¬ËAgha,ââ¬â¢ Amir ââ¬Å"wondered briefly what it might be like to live with such an ingrained sense of oneââ¬â¢s place in a hierarchy. â⬠(Hosseini 28) Yet he himself lives in such a way as to lose himself ââ¬â his self worth and reliance by conforming to society and its customs. For many years, Amir feels as though he and Hassan are adversaries for Babaââ¬â¢s love and he is envious of this, together with Hassanââ¬â¢s abilities: ââ¬Å"Hassan made his stone skip eight times. The most I managed was fiveâ⬠¦ Baba â⬠¦patted Hassan on the back. Even put his arm around his shoulder. â⬠(Hosseini 8-9) Amir greatly desires his fatherââ¬â¢s acceptance and approval and very seldom receives it. He overhears his father say that ââ¬Å"thereââ¬â¢s something missing in that boyâ⬠and that he believes ââ¬Å"a boy who wonââ¬â¢t stand up for himself becomes a man who canââ¬â¢t stand up to anything. â⬠(Hosseini 15) Amir decides ââ¬Å"there was no other viable optionâ⬠than to ââ¬Å"win that winterââ¬â¢s tournament,â⬠and ââ¬Ërun that last kite. â⬠(Hosseini 38) He believes that his ââ¬Å"life as a ghost in this house would finally be overâ⬠and that he would show Baba ââ¬Å"once and for all that his son was worthy. â⬠(Hosseini 38) On winning the race, he experiences the ââ¬Å"greatest moment of [his] twelve years of life, seeing Baba on that roof, proud of [him] at last. â⬠(Hosseini 45) Following Hassan, who has gone running for the kite, Amir wants ââ¬Å"to make a grand entrance, a hero, prized trophy in [his] bloodied hands. â⬠(Hosseini 46) He finds Hassan ââ¬Å"standing at the end of a blind alleyâ⬠(Hosseini 49) blocked by Assef and his two friends. But rather than help Hassan, even after seeing the ââ¬Å"look of the lambâ⬠(Hosseini 53) on Hassanââ¬â¢s face Amir runs, telling himself that ââ¬Å"I was a cowardâ⬠ââ¬Å"afraid of Assef and what he would doâ⬠ââ¬Å"afraid of getting hurtâ⬠(Hosseini 53) but in reality it is ââ¬Å"the price [he] had to pay, the lamb [he] had to slay, to win Baba. His reasoning ââ¬Å"He was just a Hazara, wasnââ¬â¢t he? â⬠(Hosseini 54) After the rape, Hassanââ¬â¢s very existence infuriates and irritates Amir because it reminds him of his cowardice ââ¬â his guilt. He tries to forget what he has done to Hassan and treats him like a servant instead of a friend; he lies about him being ill ââ¬Å"heââ¬â¢s got a cold or something,â⬠(Hosseini 56) he hits him with ripe pomegranates, he asks his father ââ¬Å"have you ever thought about getting new servants? ââ¬â¢ (Hosseini 61) Finally he frames Hassan for theft and Hassan again takes the blame rather than reveal Amir for what he is. Nothing works however, because he cannot discard his guilt as easily as he can discard Hassan himself. Even after later leaving Afghanistan for America with his father, he is never really able to forget and later he realizes you can bury the past but that it ââ¬Å"claws its way out. â⬠He realizes that he has been ââ¬Å"peeking into that deserted alleyâ⬠where Hassan was raped ââ¬Å"for the last twenty six years. â⬠(Hosseini 2) After returning to Afghanistan and learning of Hassanââ¬â¢s death and his orphaned son Sohrab, Amir endeavours to right his wrongs ââ¬â ââ¬Å"there is a way to be good againâ⬠(Hosseini 2) by locating Sohrab, who is in fact his nephew. He finds Sohrab in the hands of Assef, now a Talib, and being used as a sexual plaything. This illustration of manââ¬â¢s inhumanity to man, gives evidence to Emersonââ¬â¢s belief, that ââ¬Å"the differences among the members of a race are greater than the differences between races. â⬠(The Internet Encyclopedia of Philosophy) Amir must fight and defeat Assef if he is to redeem himself and his past; thus Amir finds his strength of character, the inner strength that he had all along, but believed was somehow missing ââ¬â Emersonââ¬â¢s ââ¬Ëself relianceââ¬â¢ and ââ¬Ëtrust in himself. ââ¬â¢ Ironically however, it is Sohrab who saves Amir in just the same way as his father Hassan had saved him before ââ¬â with his slingshot. Amirââ¬â¢s lack of self-acceptance, his desire to win his fatherââ¬â¢s heart and his envy of Hassan causes him to live his life conforming to an unjust and class conscious society. He places blame on Hassan for the lack of his fatherââ¬â¢s love and blame on himself for his conformity and the terrible injustice he has caused on Hassan. According to Emerson, one must be able to find a ââ¬Å"blameless livingâ⬠if they are to be a ââ¬Å"whole man,â⬠(The Internet Encyclopedia of Philosophy) and Amir clearly illustrates his lack of living blamelessly. Just as Hassan was socially alienated, so to is David, in ââ¬ËGiovanniââ¬â¢s Room,ââ¬â¢ wherein he is faced with a choice between his American fiancee (value set) and his European boyfriend, so ultimately he must grapple with being alienated by the culture that produced him. In other words, does he conform or does he not? Does he be honest with his true self and be reliant on himself? David, unlike Hassan, takes the easy way out and marries Hella. David has been running from himself since his first sexual encounter as a teenager, with Joey, and although he has a profound connection with Joey, he deserts him and spurns his friendship afterwards. In other words, like Amir he conforms rather than live with ââ¬Å"the integrity of his own mind. â⬠(Emerson 2). He becomes what Emerson terms as an ââ¬Ëimitatorââ¬â¢ and lives a life of deceit and denial. Although mixing with the gay crowd, he proclaims his heterosexuality. Later he meets Giovanni and they fall in love. Afraid to commit to Giovanni he has a one night stand with Sue, another American lost in Paris. As with Joey, David deserts Giovanni, whereupon Giovanni goes into a downward spiral and because of lies, false promises, abuse and humiliation he eventually kills and is sentence to death by the guillotine. Giovanni dies because of the people around him; they are envious of his beauty, openness and inward freedom; they pretend to be what they are not ââ¬Ëimitatorsââ¬â¢. David remains forever trapped in his own ââ¬Ëroomââ¬â¢, closet, or hell of his irreconcilable identity. (Zaborowska, M. J. 1) He fails in his journey of self-discovery within a society where gender, race and sexuality impacts on national identity. David remains loyal to America, the land of the free but never finds happiness, becoming emotionally dead and hollow, unable to love others, but mostly himself. In summary, we can recognize the lack of Emersonââ¬â¢s concept of self-reliance in the pivotal characters of Amir and Baba in ââ¬ËThe Kite Runnerââ¬â¢ and David in ââ¬Å"Giovanniââ¬â¢s Room,â⬠while at the same time we see evidence of nonconformity to social standards by Hassan and Giovanni. ââ¬Å"High be his heart, faithful his will, clear his sight, that he may in good earnest be doctrine, society, law, to himself. â⬠(Emerson 10) References Baldwin, J. Giovanniââ¬â¢s Room. Dell Publishing, NY. 1956 Emerson, R. W. Essay II Self Reliance 1841 As published on http://www. emersoncentral. com/selfreliance. htm Hosseini, Khaled The Kite Runner courtesy of Shahid Riaz, 2003 http://esnips. com/UserProfileAction. ns? id+ebdaae62-b650-4f30-99a4-376c0a084226 The Internet Encyclopedia of Philosophy Ralhp Waldo Emerson (1803-1882) http://www. iep. utm. edu/e/emerson. htm December 6, 2008 Zaborowska, Magdalena J. University of Michigan. 2003 http://www. litencyc. com/php/sworks. php? rec=true&UID=4964
Wednesday, October 9, 2019
Bone and Joint Histology
* It is a specialised connective tissue. * Osteogenic cells ââ¡â osteoblast (makes matrix, active when young, and after fracture) ââ¡â osteocyte ââ¡â osteoclast (functions in resorption, breakdown of bone matrix) (makes cavities) (from blood monocyte) Bone Functions * Framework for support of the skeleton * Protection: brain, spinal cord, lungs and heart * Levers for muscles attached to them via tendons * Reservoir for minerals e.g. calcium, magnesium, phosphates etc. Bone Matrix * Components * Extracellular matrix (ground substance and fibres) consists of inorganic material (65%) e.g. calcium phosphate, calcium carbonate, magnesium, sodium, potassium, bicarbonate, fluoride, citrate, sulfate, and hydroxide. * Minerals give bone hardness and rigidity * Organic component (35%) mostly type I collagen (95%)- gives bone slight flexibility; and ground substance e.g. GAGs with proteoglycans, which contain chondroitin and keratin sulfates which give bone resilience * Development 1. Bone starts as osteoid, which is collagen and GAGââ¬â¢s with no minerals 2. Bone becomes mineralised (immature, primary, or woven bone). It is the first bone to appear in development and in repair after fractures 3. Bone starts to remodel as the adult form (mature, secondary, lamellar) Bone Cells 1. Osteoprogenitor (osteogenic) cells: from embryonic mesenchyme, which differentiate into osteoblasts. Found in inner cellular layer of the periosteum, lining Haversian canals, in the endosteum (lining medullary cavity) 2. Osteoblasts: derived from osteoprogenitor cells, form and grow new bone by synthesis of organic components of bone matrix. Found on the surfaces of existing bone tissue where they deposit new bone matrix (osteoid) which contains no minerals. Later mineralization occurs, tissue is new bone. Osteoblasts extend processes with neighbouring osteoblasts for molecular transport. Sit on the edge of bone. 3. Osteocytes: flat cells with small cytoplasmic processes. Aid in the maintenance of bone tissue and storage of minerals. Each osteoblast becomes surrounded by secreted matrix, once this occurs, the cell is known as an osteocyte (mature bone cell), and the space it occupies is a lacuna. Radiating out in all directions from the lacuna are tunnel-like spaces (canaliculi) which house the cytoplasmic processes of the osteocytes. The canaliculi allow transfer of nutrients, wastes between the osteocytes and blood. They are very active cells. Communicate via cytoplasmic processes in the canaliculi, metabolic communication. 4. Osteoclasts: large motile, multinucleated cells (150 um diameter) which contain up to 50 nuclei. These cells break up and resorb bone. Osteoclasts occupy shallow depressions (Howshipââ¬â¢s lacunae). The ruffled border (infolded plasma membrane) is that part of the cell that is directly involved in the resorption of bone. It removes bone enzymatically, mineral deficiencies then the osteoclasts become active to release the minerals that have been stored in bone, hence the person becomes fracture prone. The multinuclear nature of the osteoclasts is a good identifying factor Periosteum and Endosteum * Vascular, fibrous layer surrounds bone except over articular surfaces. * 2 layers * Outer layer is collagen with some elastic fibres. This layer distributes vascular and nerve supply to bone. * Inner layer is cellular (osteogenic layer, osteoprogenitor cells), gives rise to new bone. * Central cavity of bone is lined with endosteum- thin CT composed of osteoprogenitor cells and osteoblasts. * From the outer layer of periosteum, fine bundles of collagenous fibres (Sharpeyââ¬â¢s) penetrate the underlying bone at intervals to attach the periosteum, especially at the sites of attachment of tendons and ligaments. * The periosteum contains blood vessels, nerve endings, and ligament and tendon attachments. Mature bone Organisation * Dense (compact) at the edge * This type has Haversian systems (osteons) which is a complex of 4- 20 concentric, bony circular lamellae surrounding a central (Haversian) canal (20- 100 à ¼m diameter) * The canal contains blood vessels, lymphatics, with a few unmyelinated nerve fibres, loose CT and flattened osteogenic cells and osteoblast cells that line the lumen of the canal * Osteocytes are in lacunae (in the concentric lamellae) located within or between the lamellae * A second arrangement of lamellae is found between the osteons (interstitial lamellae- formed by the collapse of old Haversian systems). These are remnants of older, partially resorbed Haversian systems. * A third arrangement (circumferential lamellae) are rings of bone around the entire bone, beneath the periosteum * Radiating from the lacunae are tiny channels (canaliculi). Processes of the osteocytes enter these canals and communicate with adjacent osteocytes where an exchange of gases occurs, nutrients are supplied to the cells and metabolic wastes are eliminated. * The Haversian canals communicate with the marrow cavity, the periosteum and with each other via the transverse Volkmannââ¬â¢s canals, which run at right angles to the long axis of the bone. Each osteon has a cement line of calcified ground substance with some collagen fibres. * Spongy (Cancelllous Bone): * This type is not organised into Haversian systems but is a meshwork of thin bars (lamellae) or trabeculae of bone lining the marrow cavity * The spaces within this latticework are filled with bone marrow. The trabeculae house osteocytes in lacunae that are fed by diffusion from the marrow cavity. Blood and Nerve Supply * Bones have periosteal vessels, which penetrate the bone of the diaphysis of long bones and divide into branches that enter the Haversian systems. These vessels supply the osteocytes embedded in the calcified matrix. * Larger vessels pierce the epiphysis to supply the spongy bone and the midshaft to supply the medullary cavity. * Small myelinated and unmyelinated nerves go into the Haversian canals. * The periosteum contains many pain fibres which makes it sensitive to injury e.g. blow to the tibia Bone Development and Growth Histogenesis (differentiation) * Bone development is mesodermal in origin and if the tissue is membrane like (a sheet of mesenchyme or loose CT), it is intramembranous bone formation * If bone replaces cartilage that is largely resorbed before bone is formed, this is endochondral (intracartilaginous) bone development. Intramembranous Bone formation * The process involves mesenchyme to bone directly (osteoblast laying bone) * Locations: flat bones, e.g. the skull, mandible, clavicle Endochondral bone formation * The process in this type of bone formation occurs in 2 steps: 1. A miniature hyaline cartilage model is formed in the region where the bone is to grow within the embryo 2. The cartilage model grows appositionally and interstitially and serves as a structural scaffold for bone development. It is then resorbed and replaced by bone (all the cartilage is replaced by bone) * Locations: long, short bones, pelvis and vertebrae Developing bone region at epiphyseal plate * Area between shaft and epiphysis is the epiphyseal plate. * Proliferation occurs at the epiphyseal aspect and replacement by bone takes place at the diaphyseal side of the plate * Growth at both ends of the bone is hormone regulated * There are a series of 5 zones beginning at the centre of the disc and go towards the diaphysis: 1. Zone of reserve cartilage (resting zone) : chondrocytes through the matrix are mitotically active producing hyaline cartilage 2. Zone of proliferation: chondrocytes proliferate and form stacks of cells that parallel the direction of bone growth. (Cartilage dies- lose blood cells- hence the bone invades the space) 3. Zone of maturation and hypertrophy (Expanding): chondrocytes mature, hypertrophy and accumulate glycogen in their cytoplasm. No mitosis occurs 4. Zone of calcification and cell death: Chondrocytes die and the cartilage matrix becomes calcified impregnated with calcium and phosphorus 5. Zone of ossification: blood vessels invade spaces left by the dying chondrocytes carrying osteoprogenitor cells from the periosteum and differentiate into osteoblasts which elaborate matrix that becomes calcified on the surface of calcified cartilage. As the matrix calcifies, some osteoblasts are entrapped as osteocytes and bone trabeculae are formed. Coalescence of trabeculae creates spongy bone. Resorption of spongy bone by osteoclasts in the centre of the diaphysis enlarges the medullary cavity. Summary of histochemical processes for both models of bone formation * Osteoblasts secrete osteoid with no minerals * Formation of primary bone whereby osteoid is mineralized * Formation of secondary bone as compact or spongy bone Growth in length of long bone * Due to interstitial growth of epiphyseal cartilage * Growth continues until around 20 when the epiphyseal plate closes (cartilage is replaced by bone) and growth in length stops Growth in width of long bone * As a result of appositional growth from the surface and resorption by osteoclasts of the inner shaft so that the marrow space can be enlarged Bone Remodelling * Continual remodelling occurs in response to forces (e.g. teeth growing jawbones). Bone is deposited due to traction and resorbed due to pressure. * In young, bone deposition exceeds bone resorption. In the adult bone deposition is balanced with resorption. Joints * Joints are classified according to the degree of movement between the bones of the joint: * Synarthroses: little or no movement. There are 3 types based on the tissue making up the union: * Syndesmosis is the union of bones by dense CT e.g tibiofibular and radioulnar joints * Synchondrosis is a junction by cartilage e.g. IVDs and symphysis pubis * Synostosis is a joint united by bone e.g. skull sutures (Starts off as fontanelles) * Diarthroidal (synovial) e.g. knee, hip, shoulder have great freedom of movement and have a CT capsule around a joint cavity held by ligaments. * The joint has an articular cartilage (hyaline) with no perichondrium. The capsule is lined (except over the articular surfaces) with a cellular, vascular, folded synovial membrane made of loose CT which secretes a viscous lubricating, synovial fluid. The viscosity of the fluid varies with temperature. *Fibrous- collagen- little to no movement- interosseous ligament *Gomphosis- tooth joined by cartilage
Tuesday, October 8, 2019
Land Rover Acquisition Essay Example | Topics and Well Written Essays - 1000 words
Land Rover Acquisition - Essay Example Tata Motors took $3bn ($2.3bn for purchasing JLR and the remainder for supplying important parts that included engine and other parts from Ford) bridge loan so as to fund this acquisition at $2.3bn with the aim of paying back a part through right issue, its stake sale in other subsidiaries and raising the rest through long term debt. The bridge loan was raised by Tata Motors, UK (which is a 100% subsidy of Tata Motors). The margin of the interest for the initial 6months on the bridge loan was 85% over LIBOR, followed by 1.2% for the following three months and then up to the end of term at 1.5% ( Gaughan, P. A. 2011). The same was intended to be pated through the rights issue, issue of securities overseas and its portfolio investments divesting. Before, Tata Motors requested to secure the funds using three simultaneous right issues, of which, of which one was o.5% convertible preference shares. However, the company was forced to share its plan for issuing the convertible preference sh ares as the prices of the share of the company fell greatly and remained low till as recent as August 2009. The other 2 rights issue (one was meant to earning Rs.21.86 billion with each other share at Rs.340/- with every share priced at Rs. 305/-) was not able to generate the expected amount of subscriptions from the share holders and required to be bailed out by companyââ¬â¢s promoters and the underwriters. Tata Motors was hoping from the past record with both Land Rover and Jaguar would be able to earn enough funds.
Monday, October 7, 2019
Provider Roles in Spiritual Care Essay Example | Topics and Well Written Essays - 1250 words
Provider Roles in Spiritual Care - Essay Example From this discussion it is clear that the spiritual dimension of the client is strongly evident during illness, stress, difficulties, and end-life-care when people strongly needed the direction and comfort derived from their spiritual preferences. Faith and religion are essential components of a clientââ¬â¢s spiritual dimension and health provider has the responsibility to have self-awareness of oneââ¬â¢s spiritual preferences before integrating a non-biased spiritual care.This paper outlines that spiritual care is the most difficult task of a provider, specially the nurses. Most of the nurses lack adequate training for spiritual care giving and may influence the provision of adequate spiritual care. Healthcare providers such as nurses need to have formal education training or graduate programs in pastoral counseling or ministry in order to provide an excellent and competent spiritual care and to refer clients to other spiritual care providers as needed. Organizational team mem bers such as the Baptist Healing Trust aim to further the work of non-profit agencies in providing health services to vulnerable populations in Middle Tennessee. Members of the Baptist Healing Trust heal with love and compassionate care in accordance with the Christian tradition. In addition, staffs of the Baptist Healing Trust have the role of reiterating the importance of meeting health needs, providing human services, and balancing of excellence in skill and great compassion. The Baptist Healing Trust operates as a funding agency and requires partnership with the staff of non-profits to raise the standard of compassionate care. The Baptist Healing Trust also offers retreats, workshops, and consultation for organizational and culture change to continue the delivery of spiritual and health services to the vulnerable and underserved population of Middle Tennessee. The Baptist Healing Trust is the organizational team member of Baptist Hospital in Nashville, Tennessee. The organizatio n believed that true healing comes from deep compassionate care and charitable health care expressed through the preservation of humanity and dignity of each human being as a creation of God (Baptist Healing Trust, 2010, n.p.). The emergence of the healing hospital in Baptist Hospital follows the teachings of Jesus and the Good Samaritan. A hospital institution does not only prevent and cure diseases but also enriched the heart and spiritual needs of client. Spiritual health provider must have a servantââ¬â¢s heart that offers compassionate care, goes beyond the box to meet peopleââ¬â¢s needs, has commitment to organizationââ¬â¢s values, mission, and vision, and expressed care in a continuous chain of light from care giver or provider to every patient, fellow caregiver, and one's
Sunday, October 6, 2019
Diabetes management Essay Example | Topics and Well Written Essays - 3500 words
Diabetes management - Essay Example lood glucose monitoring, oral and insulin therapies, Furthermore, the essay examines the role of multidisciplinary teams in offering patient-centered diabetic care and patients with such conditions. Lastly, the paper has critically detailed the physical, psycho-social and cultural impact of diabetes on clients and their families. The essay incorporates a case study of type 2 diabetic patient with pressure ulcers in his diabetic feet and associated conditions such as unitary and bowel incontinence, but has not adequate knowledge of management and care of his diabetic feet. The essay has adhered with ethical conduct of Nurses and Midwifes since the identity of the patient has been altered to John in order to protect confidential medical information of the client. The case study has been included in the appendix. Anderson and Rubin (2000) agree with Edmonds (2013) that diabetes results from several biological, environmental and lifestyle factors that lead to abnormal metabolism and hyperglycemia. Foster and Edmonds (2013) conquers with Cheyette (2005) that diabetes is a life-long condition that is associated with high glucose in the blood since the pancreas is incapable of producing enough insulin that is essential in regulating the blood sugar levels. I agree with Cheyette (2005) that John is experiencing high sugar levels due to inability to produce enough insulin. As Anderson and Rubin (2000) have outlined, insulin initiates the signal transduction whereby the glucose will enter the bloodstream for it to be stored as energy in the muscles or converted to fat by the liver. Tuomi (2005) confirms that insulin signals the liver to convert glucose to glycogen in case the body has sufficient energy. From the analysis, I believe insufficient of insulin affects metabolism processes in the body of John. The Health Commission (2007) explains that some critical pathophysiological aspects of type 2 diabetes include impaired secretion of insulin and increased body resistance
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